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Bedbugs: Symptoms, Causes, and How to Get Rid of Them

Oct 12
9 min read

Updated: 3 days ago

Medically reviewed by Dr. Baraa Alnahhal, MD · Last reviewed: October 17, 2026

Quick Answer

Bedbugs are small, reddish-brown, blood-sucking, wingless insects about the size of an apple seed that hide near sleeping areas and feed on humans at night. They are not known to transmit disease, though bites can cause allergic or skin reactions. Signs include clustered itchy bites and dark specks on mattress seams. Professional extermination is recommended for infested homes.

What the research says

  • Bedbugs carry pathogens but have not been shown to pass them to people. A systematic review of clinical and laboratory studies from 1990 to 2016 noted that upwards of 45 disease pathogens have been reported in bedbugs, yet concluded that no published study has demonstrated a causal relationship between bedbugs and infectious disease transmission in humans (Lai et al., Arch Dermatol Res, 2016) [6].

  • There is little trial evidence for bite treatments. A JAMA review of 53 articles found only 2 clinical trials on bedbugs (both testing pest control), little evidence that bedbugs are vectors of communicable disease, and no evidence that outcomes differ significantly between people treated for bite reactions and those who received no treatment (Goddard and deShazo, JAMA, 2009) [7].

  • Bite reactions resolve on their own, but eradication calls for a professional. A more recent review reports that reactions to bedbug bites are self-limited, so treatment is mainly symptomatic (topical pramoxine or oral antihistamines for itching), and recommends consulting a professional exterminator to fully eradicate an infestation (Leung et al., Curr Pediatr Rev, 2024) [8].

What are bedbugs?

Bedbugs are small, reddish-brown, blood-sucking, wingless insects. They are oval and flat, and about the size of an apple seed. During the day, they hide in the cracks and crevices of beds, box springs, headboards, bed frames, and other objects near the bed. At night, they come out to feed on their preferred host: humans.

The good news first. Bedbugs can bite, but they are not known to spread disease. Bedbug bites usually clear up without treatment in a week or two. In some people, however, the bites can cause an allergic reaction or a severe skin reaction.

The risk of running into bedbugs is higher in places where nighttime guests come and go often, such as hotels, hospitals, and homeless shelters. If bedbugs have moved into your home, professional extermination is recommended.

A calm bedroom scene where a woman inspects a mattress seam with a small flashlight in soft morning light, luggage resting on a dresser nearby. Image: rinnit.com – rinnit.com
Inspecting a mattress seam is the fastest way to confirm or rule out bedbugs before they spread.

At a glance: bedbugs in numbers and facts

Aspect

What the evidence shows

What they are

Small, reddish-brown, wingless, blood-sucking insects

Shape and size

Oval and flat, about the size of an apple seed

When they feed

At night, primarily on humans

Where they hide

Cracks and crevices of beds, box springs, headboards, bed frames

Do they spread disease

No, but bites can cause allergic or severe skin reactions

Bite healing time

Usually clear up without treatment in a week or two

Survival without food

Can live months without eating

Recommended home response

Professional extermination

What are the symptoms of bedbug bites?

Bedbug bites can be difficult to tell apart from other types of insect bites and rashes. They are usually itchy and may appear clustered together or lined up in rough rows.

The bites themselves typically have a few recognizable features. They are inflamed spots, often with a darker spot in the middle. They are usually located on the face, neck, arms, and hands, because those areas are most exposed during sleep.

Reactions vary widely from person to person. Some people have no reaction to bedbug bites at all. Others experience an allergic reaction that can include severe itching, blisters, or hives.

Symptom

What it looks like

Itchiness

Bites are usually itchy

Arrangement

May appear clustered or lined up in rough rows

Spot appearance

Inflamed spots, often with a darker spot in the middle

Typical locations

Face, neck, arms, and hands

Allergic reaction

Severe itching, blisters, or hives

No reaction

Some people react not at all

When to see a doctor

If you experience allergic reactions or severe skin reactions to bedbug bites, see your health care provider for professional treatment. This includes blisters, hives, or itching that feels out of proportion to a small bite.

What causes bedbug infestations?

Bedbug infestations may be linked to three broad factors: more frequent travel, changes in pest control practices, and insecticide resistance. As people travel more and as bedbugs develop resistance to some older insecticides, infestations have become harder to prevent and control.

Infographic: what a bedbug looks like, signs of an infestation, and how to get rid of them, in three labeled columns with icons. Image: rinnit.com – rinnit.com
Three steps in one view: what a bedbug looks like, the signs that confirm an infestation, and the proven ways to eliminate them.

Where do bedbugs hide?

Bedbug infestations usually occur around or near where people sleep. Beyond the bed itself, check clothing, luggage, bedding, boxes, box springs, mattresses, headboards, and other objects near the bed.

Bedbugs also hide in less obvious places. They can be found under peeling paint and loose wallpaper, under carpeting near baseboards, in the seams of upholstered furniture, and under light switch plates or electrical outlets.

Hiding area

Examples

Around the bed

Box springs, mattresses, headboards, objects near beds

Personal items

Clothing, luggage, bedding, boxes

Wall coverings

Under peeling paint and loose wallpaper

Flooring edges

Under carpeting near baseboards

Furniture

Seams of upholstered furniture

Electrical fixtures

Under light switch plates or electrical outlets

How do bedbugs spread?

Bedbugs can move from one site to another by traveling on items such as clothing, luggage, furniture, boxes, and bedding. They can also travel easily between floors and rooms in hotels or apartment buildings.

Do bedbugs mean a home is dirty?

No. Bedbugs do not care whether their environment is clean or dirty. All they need is a warm host and plenty of hiding places. An infestation is not a sign of uncleanliness.

Who is at risk of bedbug bites?

You are at higher risk of bedbug bites if you spend time in places where people come and go often.

High-risk locations

Why the risk is higher

Hotels

Nighttime guests come and go often

Apartment buildings

Bugs travel easily between floors and rooms

Dorm rooms

Frequent turnover and shared furniture

Homeless shelters

High density of sleeping occupants

Cruise ships

Enclosed sleeping quarters, constant travel

Trains and buses

Seats used by many different riders

Refugee camps

Dense, temporary sleeping arrangements

Hospitals

Constant flow of overnight patients

How are bedbugs diagnosed at home?

Bedbugs have no lab test, so they are diagnosed by checking your home for signs of the insects. The diagnosis happens in your own home. If you suspect you are being bitten by bedbugs, immediately inspect your home for the insects. Thoroughly examine the crevices in walls, mattresses, and furniture. You may need to perform the inspection at night, when bedbugs are active.

Three signs confirm an infestation even if you never see a live bug.

Sign

What it means

Dark specks

Typically found along mattress seams, these specks are bedbug excrement

Skin castings

Bedbugs molt five times before becoming adults; the empty skins are pale yellow

Rusty or reddish stains

Small smears of blood on bed sheets where bedbugs were crushed

How are bedbug bites treated?

Bedbug bites usually do not need treatment, because they disappear on their own within a week or two. To ease symptoms, a skin cream containing hydrocortisone or an oral antihistamine such as diphenhydramine can help with itching.

Treatment

How it helps

No treatment

Bites usually disappear on their own within a week or two

Hydrocortisone skin cream

Eases itching and inflammation on the skin

Oral antihistamine (e.g., diphenhydramine)

Reduces allergic itching

If bites trigger a severe allergic reaction, see a health care provider for professional treatment.

How do you get rid of bedbugs in your home?

Getting rid of a bedbug infestation is difficult, because the insects hide well and can live for months without eating. You may need to hire a professional exterminator, who will likely use a combination of pesticides and nonchemical treatments.

Alongside professional help, several steps support the effort at home.

Vacuuming. A thorough vacuuming of crevices can remove bedbugs from an area but likely will not capture all of them. Empty the vacuum after each use so the insects do not crawl back out.

Laundering. Washing items in water that is at least 120 F (48.9 C) can kill bedbugs. Putting items in a dryer on a high setting for 20 minutes works as well.

Heat treatment in a vehicle. If you live in a very hot place, bag up the infested items and place them in a car parked in the sun with the windows rolled up for a day. The target temperature is at least 120 F (48.9 C).

Discarding items. In some cases, you may have to throw out heavily infested items such as mattresses or couches. Make it obvious the item is unusable, so no one else picks it up and gets bedbugs.

Home treatment step

Key detail

Professional extermination

Likely combines pesticides and nonchemical treatments

Vacuuming

Thoroughly vacuum crevices; empty the vacuum after each use

Laundering

Wash at 120 F (48.9 C) or dry on high for 20 minutes

Vehicle heat treatment

Bag items, park in sun for a day; target at least 120 F (48.9 C)

Discarding items

Ruin heavily infested mattresses or couches so no one else uses them

How do you prevent bedbugs?

Three habits make a real difference.

Cover up. Bedbugs do not tend to burrow under clothing. You may be able to avoid bites by wearing pajamas that cover as much skin as possible.

Inspect secondhand items. Look over used bedding, mattresses, and upholstered furniture before bringing them into your home.

Use hotel precautions. Check mattress seams for bedbug excrement when you arrive. Place your luggage on tables or dressers instead of on the floor.

Prevention habit

How to practice it

Cover up

Wear pajamas that cover as much skin as possible

Inspect secondhand items

Check used bedding, mattresses, and upholstered furniture before bringing them home

Hotel precautions

Check mattress seams for excrement; keep luggage on tables or dressers, not the floor

A traveler checks the corner of a neatly made hotel bed while an open suitcase rests on a wooden dresser in a warm hotel room. Image: rinnit.com – rinnit.com
Keeping luggage off hotel floors and checking mattress seams are the two highest-value travel precautions.

What is the bottom line on bedbugs?

Bedbugs are a nuisance, not a health emergency. They are not known to spread disease, and their bites usually heal on their own within a week or two. The real problem is how persistent they are. They hide deep in crevices, survive months without food, and travel silently on luggage and furniture.

The fastest path to a clear home runs through professional extermination, supported by heat-based laundering, careful vacuuming, and, in some cases, discarding heavily infested furniture. Trying to fight an infestation with DIY methods alone often leaves hidden pockets of bugs that return weeks later.

Prevention is simpler than elimination. Cover up at night, inspect secondhand furniture before it enters your home, and keep luggage off hotel floors while checking mattress seams on arrival. These small habits stop most problems before they start.

The best next step depends on what you are dealing with. If you have itchy bite clusters, inspect your mattress seams tonight. If you find dark specks, pale yellow skins, or rusty stains, book a professional exterminator promptly. And if your bites blister or cause hives, see a health care provider for treatment.

Take the next step: Itchy bites that keep coming back deserve a closer look. Inspect your mattress seams tonight, and talk to a health care provider if bites blister or cause hives.

FAQ

Do bedbugs spread disease?

No. Bedbugs are not known to spread disease, but their bites can cause allergic reactions or severe skin reactions in some people, including blisters and hives.

What do bedbug bites look like?

Bedbug bites are usually itchy, inflamed spots, often with a darker spot in the middle. They tend to be clustered or lined up in rough rows, most often on the face, neck, arms, and hands.

How do I know if I have bedbugs?

Inspect your home immediately: check mattress seams for dark specks of excrement, look for pale yellow molted skins (bedbugs molt five times before adulthood), and look for rusty or reddish blood smears on sheets where bugs were crushed.

How long do bedbug bites last?

Bedbug bites usually disappear on their own within a week or two and typically do not need treatment, though hydrocortisone cream or an oral antihistamine can ease itching.

Can I get rid of bedbugs myself?

Vacuuming and hot laundering help, but professional extermination is recommended for an infested home because bedbugs hide well and can live months without eating. DIY methods rarely reach all hiding spots.

Disclaimer: This article is for general informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional or licensed pest professional for individual questions.

References

  1. Mayo Clinic Staff. Bedbugs - Symptoms and causes. Mayo Clinic. January 5, 2024. https://www.mayoclinic.org/diseases-conditions/bedbugs/symptoms-causes/syc-20370001

  2. Mayo Clinic Staff. Bedbugs - Diagnosis and treatment. Mayo Clinic. January 5, 2024. https://www.mayoclinic.org/diseases-conditions/bedbugs/diagnosis-treatment/drc-20370005

  3. US Environmental Protection Agency. How to Find Bed Bugs. US EPA. Updated September 8, 2026. https://www.epa.gov/bedbugs/how-find-bed-bugs

  4. US Environmental Protection Agency. Top Ten Tips to Prevent or Control Bed Bugs. US EPA. Updated August 19, 2026. https://www.epa.gov/bedbugs/top-ten-tips-prevent-or-control-bed-bugs

  5. Centers for Disease Control and Prevention. About Bed Bugs. CDC. April 26, 2024. https://www.cdc.gov/bed-bugs/about/index.html

  6. Lai O, et al. Bed bugs and possible transmission of human pathogens: a systematic review. Arch Dermatol Res. 2016;308(8):531-538. PMID 27295087. https://doi.org/10.1007/s00403-016-1661-8

  7. Goddard J, et al. Bed bugs (Cimex lectularius) and clinical consequences of their bites. JAMA. 2009;301(13):1358-1366. PMID 19336711. https://doi.org/10.1001/jama.2009.405

  8. Leung AKC, et al. Bed Bug Infestation: An Updated Review. Curr Pediatr Rev. 2024;20(2):137-149. PMID 37038684. https://doi.org/10.2174/1573396320666230406084801

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