P-Shot (Priapus Shot): Understanding the Experimental PRP Procedure

Medically reviewed by Dr. Baraa Alnahhal, MD · Last reviewed: September 2026

The P-Shot, or Priapus Shot, is an experimental medical procedure that uses platelet-rich plasma (PRP) from a patient’s own blood to potentially treat penile conditions and enhance sexual performance. While the procedure is relatively safe, scientific evidence currently lacks verification for its effectiveness in treating erectile dysfunction or increasing penis size.

Quick answer: The P-Shot is a 30-minute experimental procedure where platelet-rich plasma (PRP) is injected into the penis to theoretically promote tissue healing and blood flow. Although marketed for erectile dysfunction and sexual enhancement, there is currently no substantial scientific evidence to support these claims. The procedure costs over $1,000, is not covered by insurance, and carries minor risks like bruising and swelling. Patients should consult a urologist before proceeding.

Overview of the P-Shot Procedure

The Priapus Shot® (P-Shot®) is a specialized application of platelet-rich plasma (PRP) therapy. PRP is commonly used in sports medicine to treat injuries in muscles, joints, and tendons by utilizing the healing properties of platelets found in the blood. In the context of the P-Shot, this plasma is injected directly into the penis.

The procedure is classified as experimental because medical researchers have not yet verified how or why it might work for penile health. While some reports suggest benefits, these often come from commercial sources rather than clinical trials. Current research does not confirm that the injection improves erections or significantly alters penile tissue.

How the P-Shot Works: PRP Preparation and Theoretical Application

How the Procedure Works

The P-Shot process is relatively quick, typically taking less than 30 minutes from start to finish. It involves several distinct steps designed to isolate and apply the patient’s own healing factors.

Step	Action	Purpose
Blood Draw	A sample is taken from a vein, usually in the arm.	To obtain the raw material for the PRP.
Centrifugation	The blood is spun in a centrifuge.	To separate platelets from other blood components.
Preparation	PRP is drawn into a sterile syringe.	To create the concentrated injection.
Numbing	Local anesthetic or cream is applied to the penis.	To minimize discomfort during the injection.
Injection	PRP is injected into specific areas of the penis.	To deliver the platelets to the target tissue.

Claimed Uses and Scientific Evidence

Many claims surround the P-Shot, particularly regarding its ability to treat specific conditions. However, it is essential to distinguish between advertised benefits and what scientific research currently supports.

Condition	Claimed Benefit	Scientific Status
Erectile Dysfunction	Improved erection quality and duration.	Scientific evidence shows it cannot treat ED.
Peyronie’s Disease	Reduction of scar tissue and curvature.	No good scientific evidence currently available.
Lichen Sclerosus	Relief from itching and skin irritation.	No good scientific evidence currently available.
Penis Size	Increased length and girth.	Claim not supported by scientific evidence.
Sexual Performance	Increased sensation and ejaculation control.	No scientific evidence to support these claims.

Consulting a Specialist About the Experimental P-Shot

Risks, Recovery, and Considerations

While the P-Shot is considered relatively safe because it uses the patient’s own blood, there are still potential side effects and practical considerations to keep in mind.

Potential Risks

The most common side effects are minor and typically resolve on their own. These include:

• Bruising at the injection sites.

• Temporary swelling or discoloration (red, purple, or dark brown).

• A small risk of infection, as with any injection.

• Pressure or discomfort as the numbing agent wears off.

Recovery and Follow-up

Most individuals can return to their normal daily activities immediately after the procedure. A follow-up appointment is generally recommended a few weeks later to assess any response to the treatment. Because there is no standardized protocol, the frequency of shots varies, with some providers recommending yearly treatments.

Cost and Professional Guidance

The P-Shot is an out-of-pocket expense, with estimates often exceeding $1,000 per injection. It is not covered by health insurance. Before deciding on the procedure, it is advisable to consult a primary care physician or a urologist who specializes in sexual health. It is also crucial to verify the qualifications of the provider, as many who advertise the service may not be experts in penile health.

A Safe, Sterile Setup for PRP Procedures

Conclusion

The P-Shot remains an experimental option for those seeking to address penile-related conditions or enhance sexual performance. While the use of PRP is established in other medical fields, its application in sexual health lacks the clinical evidence necessary to guarantee results. Patients should maintain realistic expectations and prioritize consultations with qualified medical experts.

Next Steps

1. Consult a Urologist: Speak with a specialist to discuss proven treatments for erectile dysfunction or other penile conditions.

2. Verify Provider Credentials: If choosing the P-Shot, ensure the practitioner has extensive experience in sexual health.

3. Compare Options: Research other treatments that have more substantial clinical backing and predictable outcomes.

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Frequently Asked Questions

Is the P-Shot a permanent solution?

There is no data to suggest the results are permanent; some providers recommend yearly injections.

Does the P-Shot hurt?

Numbing agents are used to minimize pain, though some pressure or discomfort may be felt.

Can the P-Shot increase my penis size?

Current scientific evidence does not support the claim that the P-Shot increases length or girth.

Is the P-Shot covered by insurance?

No, insurance companies do not cover the P-Shot as it is considered experimental.

How long does the procedure take?

The entire process usually takes less than 30 minutes.

What is the main ingredient in a P-Shot?

The injection consists of platelet-rich plasma (PRP) derived from your own blood.

Are there any major risks?

The procedure is relatively safe, with minor risks like bruising, swelling, and infection.

When will I see results?

Results vary; some see changes in days, others in months, and some see no change at all.

Can I drive home after the procedure?

Yes, most patients can return to normal activities immediately.

What is the difference between a P-Shot and an O-Shot?

The P-Shot is for penile health, while the O-Shot is a similar experimental PRP injection for vaginal conditions.

Do I need to prepare for the appointment?

No special preparation is needed, but comfortable clothing is recommended.

Is there scientific proof that it treats ED?

No, scientific evidence currently shows that the P-Shot cannot treat erectile dysfunction.

Who should I talk to about getting a P-Shot?

It is best to start with your primary care physician or a urologist.

How much does a single P-Shot cost?

Estimates are typically over $1,000 per injection.

What does a centrifuge do in this process?

It spins the blood sample at high speeds to separate the platelets from other components.

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Medical Disclaimer: This information is for educational purposes only and does not constitute medical advice. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.